Artery and vein — direction of flow
Artery: carries blood away from the heart, at high pressure because it receives blood directly from the contraction of the ventricles. Vein: carries blood towards the heart, at low pressure because that blood has already been through the narrow capillaries. Both terms describe direction relative to the heart, never what the blood contains. The full wall, lumen and valve comparison is in the structure table above.
Capillary — the exchange vessel
Capillary: the smallest vessel, linking arteries to veins. Its wall is one cell thick, giving the shortest diffusion distance, and its lumen is about one red blood cell wide, so cells pass in single file close to the wall. The walls are permeable — small molecules cross through gaps between the wall cells. Capillary beds give a very large total surface area, and blood flows through them slowly, so there is time for exchange in both directions.
(Extended) Pressure, valves and the named vessels
Arteries: thick walls with muscle to withstand the high-pressure surge, plus elastic fibres that stretch as blood is forced in and recoil between beats, smoothing the pulse and maintaining forward flow. Veins: thin walls with little muscle, but valves at intervals that close to stop backflow, keeping low-pressure blood moving towards the heart even against gravity in the limbs. The four named vessels are tabulated in the note.
Drawn from real examiner reports.
(Extended) "High pressure" is not an explanation
An explain question wants the wall features, not a restatement of the function. Say the wall is thick and muscular so it withstands the pressure without bursting, and elastic so it stretches as blood is forced in and recoils between beats, maintaining pressure and smoothing the pulse. Writing only that arteries carry blood at high pressure stops short of the marks.
Flagged Jun 2022 P41 Q1ci · Nov 2023 P43 Q1bi
(Extended) "Artery" is not a vessel name
When a diagram or scenario asks you to name a vessel, an unqualified artery or vein earns nothing. Give the full name: aorta (left ventricle to body), vena cava (body to right atrium), pulmonary artery (right ventricle to lungs), pulmonary vein (lungs to left atrium). Name the vessel even when the question seems to accept a general term.
Flagged Jun 2022 P31 Q1c · P32 Q7c
(Extended) "For exchange" with no reason
Naming the function is only half the answer. The credited link is structural: the wall is one cell thick, so the diffusion distance between blood and tissue cells is short, and diffusion is faster over a shorter distance. "Capillaries let substances move between blood and cells" scores poorly alone — pair the feature with its consequence every time.
Flagged Jun 2022 P41 Q1ciii · Nov 2022 P32 Q4c
(Extended) Pulmonary vessels break the rule
"Arteries carry oxygenated blood" is a systemic-circulation habit, not a definition. The pulmonary artery flows away from the heart, so it is an artery, but its blood is deoxygenated on the way to the lungs. The pulmonary vein flows towards the heart, so it is a vein, but its blood is oxygenated. Classify by direction first, then check for the lung connection.
Oxygenation is not a structure
Asked for structural differences between an artery and a vein, many candidates answer that one carries oxygenated and the other deoxygenated blood. That is a difference in contents, not in structure, and earns nothing. Structural answers are wall thickness, lumen diameter relative to the wall, the presence of valves, and the amount of muscle and elastic tissue.
(Extended) Aorta and pulmonary artery swapped
The two vessels leaving the ventricles are easy to confuse, and so are the two entering the atria. Fix them by side: the aorta leaves the left ventricle and the pulmonary artery leaves the right ventricle; the pulmonary vein enters the left atrium and the vena cava enters the right atrium. Left side of the heart carries oxygenated blood, right side deoxygenated.
A capillary is not a small artery
Capillaries are a distinct vessel type, not scaled-down arteries or veins. They have no muscle or elastic tissue and no valves, because they never have to withstand pressure or prevent backflow — their whole structure serves exchange instead. In a cross-section their wall is a single layer of cells, not a thinner version of an artery wall.
(Extended) Use the three-part chain
Feature, then mechanism, then function. Valves at intervals along a vein -> they close if blood starts to flow backwards -> low-pressure blood keeps moving one way, towards the heart. Every explain question in this leaf fits that chain, so build the answer in that order.
(Extended) Name a vessel in two steps
First ask which way the blood flows relative to the heart: away is an artery, towards is a vein. Only then check whether the vessel connects to the lungs, because the two pulmonary vessels reverse the usual oxygenation pattern. Never start from whether the blood is oxygenated.
Check your cross-section drawing
Artery: thick muscular wall, comparatively narrow lumen, no valves. Vein: thin wall, wide lumen, valves drawn at intervals. Capillary: a single layer of cells. Keep the relative wall thicknesses consistent across the whole diagram, and never draw valves on the artery.
Wall percentage: divide the right way
Wall thickness ÷ external diameter × 100, not the other way up, and do not drop the ×100. A high percentage means a thick wall and narrow lumen, so an artery; a low one means a thin wall and wide lumen, so a vein. Always finish by naming the vessel the figure implies.
Cambridge 0654 spec reference: Section B9 "Transport in animals", sub-topic B9.3 "Blood vessels". Covers the structure of arteries, veins and capillaries (Core), the function of capillaries (Core), and (Extended) how structure relates to blood pressure, how capillary structure relates to function, and the named vessels to and from the heart and lungs.
Artery -- a blood vessel that carries blood away from the heart, usually at high pressure.
Vein -- a blood vessel that carries blood towards the heart, usually at low pressure.
Capillary -- the smallest blood vessel, linking arteries to veins, with a wall only one cell thick; its function is the exchange of substances (e.g. oxygen, glucose, carbon dioxide, waste products) between the blood and body tissue cells.
Structural comparison (Core):
| Feature | Artery | Vein | Capillary |
|---|---|---|---|
| Wall thickness | Thick | Thin | One cell thick |
| Lumen diameter | Narrow (relative to wall) | Wide (relative to wall) | Very narrow (~1 red blood cell wide) |
| Valves | Absent | Present, at intervals | Absent |
| Muscle/elastic tissue | Large amount | Small amount | None |
(Ext) Structure-pressure link: arteries have thick, muscular, elastic walls to withstand and maintain high blood pressure; veins have thin walls and rely on valves to prevent backflow of low-pressure blood.
(Ext) Named major vessels:
| Vessel | Direction | Route | Oxygenated? |
|---|---|---|---|
| Aorta | Away from heart | Left ventricle -> body | Yes |
| Vena cava | Towards heart | Body -> right atrium | No |
| Pulmonary artery | Away from heart | Right ventricle -> lungs | No |
| Pulmonary vein | Towards heart | Lungs -> left atrium | Yes |
Define "capillary".
(a) Describe TWO structural differences between an artery and a vein. (2 marks)
(b) State ONE structural feature of a capillary wall that is different from both an artery and a vein wall. (1 mark)
(c) State the function of capillaries. (2 marks)